[Asp5]-Oxytocin_product_DataBase

Bioactivity

[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin causes uterine contractions in vitro, enhanced by Mg2+. [Asp5]-Oxytocin has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic[1].

Invitro

[Asp5]-Oxytocin 不仅对子宫张力受体具有高亲和力，而且具有与催产素相同的内在活性[1]。[Asp5]-Oxytocin 对子宫的收缩作用可被 1 mM Mg2+ 增强[1]。[Asp5]-Oxytocin 分别发挥与 20.3、41 和 0.14 单位/毫克的剂量的大鼠子宫扩张、禽血管抑制剂和大鼠抗利尿剂相同的作用[1]。

Name

[Asp5]-Oxytocin

CAS

65907-78-0

Shortening

CYIQDCPLG-NH2 (Disulfide bridge:Cys1-Cys6)

Formula

C43H65N11O13S2

Molar Mass

1008.17

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Reference

[1]. Walter R, et al. [5-Aspartic acid]-oxytocin: first 5-position neurohypophyseal hormone analogue possessing significant biological activity. J Am Chem Soc. 1978;100(3):792-793.

PeptideDB

[Asp5]-Oxytocin

CAS: 65907-78-0 F: C43H65N11O13S2 W: 1008.17